ESRIC Super-Resolution Summer School 2018
The ESRIC super-resolution summer school is a five-day residential course held in Edinburgh. The course is designed to give participants a thorough grounding in super-resolution microscopy in an informal and intimate setting. It brings together leading academics and the major suppliers of super-resolution microscopes to provide expertise and guidance in the theory and practise of structured illumination microscopy (SIM), stimulated emission depletion microscopy (STED), AiryScan and single molecule localization microscopies (PALM, sptPALM and dSTORM).
This year we will be running workshops with the latest technology from Leica, Zeiss, Nikon, ONI, Hamamatsu and Andor. We also have speakers joining us from across the globe to discuss their pioneering research, including Silvio Rizzoli, Christian Eggeling, Sara Abrahamsson, Jonathan Grimm and Ricardo Henriques.
The summer school will consist of informal lectures and workshops and participants will have ample time to gain project specific advice from all of the academic experts and suppliers through dedicated Q&A sessions and informal social events. The course is suitable for anyone with prior experience of fluorescence microscopy looking to exploit the benefits of super-resolution microscopy in their research.
Please scroll down the page to find further information about the course and to submit your application.
The Edinburgh Super-Resolution Imaging Consortium (ESRIC)
ESRIC: An open-access advanced imaging facility specialising in super-resolution with a focus on interdisciplinary collaboration and teaching. The Edinburgh Super-Resolution Imaging Consortium represents the coming together of expertise across a broad scientific spectrum from cell biologists to physical scientists with the aim to extend the boundaries of cellular imaging beyond diffraction limits in order to investigate cellular functions and human disease.Find out more about ESRIC and what they offer
As part of the application process, delegates are required to write a letter of motivation, describing your current use of microscopy, how you hope to use super-resolution in the future in your research and what you hope to gain from the course. This information will then be used as a basis for selection for the course.
There are 36 places on the course and applications are processed through a rolling admission. The rolling admission dates are as follows:
Round 1 - 12 December to 31 December
Round 2 - 1 January to 31 January
Round 3 - 1 February to 28 February
There is no quota for each round and as delegates will be selected based on their letter of motivation and application, it is possible the course will fill up within the first round so it is recommended that you apply as soon as possible to avoid disappointment. Delegates will be contacted after each round of applications confirming a place, if selected.
- 09:00Intro to Super-Resolution Microscopy (SR)
- 09:45Poster Session 1
- 10:30Sample Preparation in SR Microscopy
- 13:15Single Molcule Localisation Microscopy
Sebastian Van De Linde
- 14:45Poster Session 2
- 15:30Structured Illumination Microscopy
- 17:00Q&A over wine and canapes
- 18:30Depart for Dinner at The Dome
- 21:00Optional walking tour / Stay forcoffee at the dome
- 09:00Dyes for SR
- 10:30Coffee Break
- 11:00SR Analysis
- 13:45Stimulated Emission Depletion Microscopy
- 15:45Bio-application and SR
- 17:15Q&A over wine and canapes
- 18:30End of day
The final 3 days of the course are workshop based in smaller groups. An individual’s timetable may vary from the specified order below as groups rotate through all the sessions.
- 09:00STED -
- 12:00Lunch and Bitesize workshops
- 17:00End of day
- 09:00dSTORM and single-molecule FRET
- 12:00Lunch and Bitesize workshops
- 19:00Course Dinner at the Scottish Cafe
- 09:00iSIM Workshop
- 13:30SRRF Workshop
Andor and Ricardo Henriques
- 17:00End of day
End of Course
Dr Alison Dun
Alison is the facility manager for the Edinburgh Super-Resolution Imaging Consortium (ESRIC) and is based at the Heriot-Watt University site. Alison completed her PhD at the University of Edinburgh in 2013 where she used a wide range of advanced imaging techniques to study cell membrane biology. Alison now works in an interdisciplinary environment, running the imaging facility at the Institute of Biological Chemistry, Bioengineering and Biophysics at Heriot-Watt University.
Dr Ann Wheeler
University of Edinburgh
Ann is a cell biologist and our University of Edinburgh ESRIC facility manager with expertise in advanced light microscopy in particular in Structured Illumination Microscopy (SIM) and Single Molecule Localisation Super-resolution microscopy (SMLM) as well as quantitative image analysis. Ann works with collaborators in the generation of new methods and methodologies for visualising structures by super-resolution.
University of Oxford
Christian Eggeling holds a PhD in Physics from the University of Göttingen, where he optimized single-molecule detection. From 2000 to 2003 he was a research scientist at Evotec, Hamburg, developing advanced fluorescence microscopy techniques for high-throughput drug screening. In 2003, Christian joined the MPI of Biophysical Chemistry, Göttingen as a senior scientist in the department of Professor Stefan Hell (2014 Nobel Laureate in Chemistry). Here, he was focused on the field of optical super-resolution microscopy, specifically the biological applicability of stimulated emission depletion (STED) microscopy. Since 2012, Christian has been a principal investigator in the Human Immunology Unit and the scientific director of the Wolfson Imaging Centre at the Weatherall Institute of Molecular Medicine, Oxford University. In 2014, as a Professor of Molecular immunology Christian’s research has been focused on advanced microscopy for the investigation of immune cells and cellular plasma membrane organization.
Dr Ricardo Henriques
University College London
Ricardo is a nano biophysicist, basing his research on the development of experimental imaging technology to study biological processes that fall outside the resolving power of conventional microscopes. He did his PhD between the IMM (Lisbon, Portugal), Institut Pasteur (Paris, France) and CSIR (Pretoria, South Africa), developing super-resolution optical and analytical approaches. In 2011 he joined the Institute Pasteur as a postdoc where he applied experimental super-resolution microscopy to study cell signalling and HIV-1 host-pathogen interactions. In 2013 he was appointed group leader at UCL, forming the Quantitative Imaging and Nanobiophysics research laboratory. His lab focuses in developing fundamental technologies on the areas of optical microscopy, quantitative image analysis, photoswitchable fluorescence and mapping the spatio-temporal molecular nanoarchitecture of intact cells.
The Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB)
Silvio O. Rizzoli, PhD, completed a BSc in biochemistry in 2000 at the University of Bucharest, Romania. He then carried out graduate training, until 2004, in the laboratory of Dr. William Betz at the University of Colorado. Dr. Rizzoli studied synaptic function for his PhD, and then trained as a postdoctoral fellow in the laboratory of Dr. Reinhard Jahn at the Max-Planck-Institut for Biophysical Chemistry in Göttingen, Germany, again focusing on synaptic function. Since 2007, he has led his own laboratory, first as a group leader and then as a professor at the University of Göttingen Medical Center.
Silvio’s laboratory has a dual focus – high-end imaging and cutting edge research in synaptic physiology. All projects that are run make use of advanced imaging techniques, including STED and electron microscopy.
Sebastian Van de Linde
University of Strathclyde
Sebastian van de Linde finished his PhD at the Department of Applied Laser Physics & Laser Spectroscopy, Bielefeld University, Germany, and worked with Markus Sauer as a postdoctoral researcher at the University of Würzburg. He worked as a Junior Group Leader at the Department of Biotechnology & Biophysics at the University of Würzburg before moving to The University of Strathclyde, Glasgow in 2016. Sebastian’s research interests are the development of new imaging tools and the implementation of super-resolution imaging methods in biology and medicine such as of neurobiology.
Institut des Sciences Moléculaires d'Orsay
Sandrine Lévêque-Fort is a CNRS Researcher Director at the Institute of molecular science in Orsay (ISMO). She obtained her PhD on the development of a new acousto-optic imaging approach for imaging through scattering media in the Optical Lab of ESPCI. She then became a postdoctoral fellow in the physics department of Imperial College, where she started to develop time resolved fluorescence microscopy. She joined the CRNS in 2001, when she started to develop different strategies to improve fluorescence microscopy such as plasmonics. Since 2009, her research focus on supercritical angle fluorescence microscopy and super-resolution microscopy techniques.
University of California, Santa Cruz
Janelia Research Campus
Venue for the Course
The ESRIC Summer School is based at the Heriot-Watt University, Edinburgh Campus, Edinburgh, EH14 4AS.
For more information about the University, please visit the Heriot-Watt website.
Delegates will also visit ESRIC’s second facility at the Institute of Genetics and Molecular Medicine at the University of Edinburgh during the week.
The course fees are as follows
Standard rate including 5 nights' accommodation - £850
RMS Member rate including 5 nights' accommodation - £800
Standard rate non-residential - £600
RMS Member rate non-residential - £550
Optional 6th night of accommodation on Friday 20 July for just £50.
Please note: The course will run up until 5pm on Friday the 20 July, travel to either the train station or airport will take approximately 45 minutes at that time by taxi.
Travelling to the venue
Car – There is limited parking at the campus, but we advise using public transport where possible.
Train – Edinburgh Waverley is the main train station for Edinburgh. Regular buses depart from near the station to the campus. We do not recommend alighting at either Edinburgh Park or Curriehill as there is no direct transport link to the campus from these stations.
Air - Edinburgh International Airport is served by scheduled national and international flights. The campus is a short journey by taxi from the airport.
The accommodation is on campus in an en-suite (double bed) student room.
Delegates can check in from Sunday 15 July.
Lunch and refreshments are included in your registration fee.
Dietary and Access requirements
The RMS is committed to our delegate’s health and wellbeing. Therefore if you have any dietary or access requirements please contact Karina Lang.
Registration will be taking place on Monday morning from 08.15 – 08.45.
Andor Technology plc is a global leader in the pioneering and manufacturing high performance scientific imaging cameras, spectroscopy solutions and microscopy systems for research and OEM markets. Andor has been innovating the photonics industry for over 20 years and aims to continue to set the standard for high performance light measuring solutions that allow consumers to perform light measurements previously considered impossible. Through continuous dialogue with customers and strong teamwork, Andor continues to innovate ground-breaking products that improve the world in which we live.
Carl Zeiss Microscopy Ltd
Carl Zeiss is an innovative technology leader in the fields of optics, precision engineering and electronic visualisation. Time and time again, we set new, pioneering standards in sophisticated technology for recognising, experiencing, measuring, analysing, structuring and processing a wide spectrum of objects. With professional optics we meet the expectations of even our most critical customers - not only in the fields of research, medicine, industry, but also for use in leisure activities.
Hamamatsu Photonics is a world-leading manufacturer of opto-electronic components and systems and employs over 3000 staff worldwide. The corporate headquarters are based in Hamamatsu City, Japan along with various manufacturing plants and central research laboratories. Since its inception in 1953, Hamamatsu Photonics has expanded to now enjoy a global presence throughout Asia, Europe and North America.
Hamamatsu Photonics’ corporate philosophy stresses the advancement of Photonics through extensive research and development. Hundreds of new opto-electronic products are introduced to the market each year and many Hamamatsu products are regarded as state-of-the-art. Hamamatsu sources, detectors and imaging products are designed to cover the entire optical spectrum, from nuclear radiation, x-ray, Ultraviolet (UV), Visible and Infrared radiation. Hamamatsu devices provide solutions for a wide variety of applications including analytical, industrial and medical instrumentation.
Leica UK Ltd
Leica Microsystems is a leading manufacturer and supplier of high precision optical solutions based on microscopes and related instruments. The company manufactures a comprehensive portfolio of products used in a wide variety of areas requiring vision, measurement and analysis, including applications in the life sciences (such as bio-technology research and medicine) and the material sciences.
Nikon UK Ltd
Nikon Instruments is a leading manufacturer in light microscopy and metrology solutions. With over 90 years experience in optical design and a strong core technology group, Nikon has become a truly iconic brand for all types of imaging.
Nikon’s philosophy is to meet needs and exceed expectations. We specialise in the development of optical products, building an unbeatable reputation for lens technology and precision optics. We pride ourselves on providing high contrast, high definition, and aberration free images.
Oxford NanoImaging Limited
Oxford Nanoimaging Limited is a company originating in the Clarendon Laboratory, Department of Physics at the University of Oxford. Professor Achillefs Kapanidis and PhD student, Bo Jing, lead a collaborative, inter-disciplinary team that has pioneered innovative technologies to produce an elegant benchtop super-resolution microscope. The Nanoimager has a footprint of just 21 cm x 21 cm yet packs the capability of a much larger, conventional microscopy platform delivering super-resolution and single-molecule performance. With a significantly lower cost of entry, researchers will now be able to obtain benchtop nanoscale imaging at a fraction of the price of earlier systems without the need for a large laboratory and skilled operators. As Professor Kapanidis says, “I wish I had this when I was a graduate student.”