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DTSTART;TZID=America/New_York:20260609T100000
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LOCATION:Virtual Zoom meeting
SUMMARY:Webinar: Live Imaging of the Extracellular Matrix With a Glycan-Binding Fluorophore
DESCRIPTION:Visualizing the extracellular matrix (ECM) in real-time has long been a challenge. Dr. Kayvon Pedra’s group has developed a novel, cell-impermeant fluorophore that red-shifts and activates upon binding glycans. This allows for seamless, wash-free imaging of glycosylated ECM architecture—from in vitro models to in vivo mouse tumors—providing a powerful new tool for live fluorescence microscopy.\n
 \n
 Highlights of the presentation\n
 A cell-impermeable small molecule fluorophore turns on and red-shifts upon binding glycosylated biomolecules.\n
 Application of the dye to live biological samples enables wash-free visualization of extracellular matrix structure.\n
 Observations demonstrate no toxicity, a broad substrate profile, deep tissue penetration, and negligible photobleaching in a variety of model organisms.\n
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 <a href="https://www.bocsci.com/webinar-live-imaging-of-the-extracellular-matrix-with-a-glycan-binding-fluorophore.html">Free registration here.</a>
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