The Light Microscopy Section was founded in 1979 to cater for all optical microscopists, and especially those with an interest in innovative techniques.
Other science section
Mr Alex Sossick
Light Microscopy Section Chair
University of Cambridge
Alex heads the Imaging Facility at the Gurdon Institute, which includes a variety of microscopy techniques including confocal, high throughput and deconvolution. He is keen to raise the level of microscopy understanding and application, and runs and takes part in various microscopy courses.
Prof Gail McConnell
Light Microscopy Section Secretary
University of Strathclyde
Gail McConnell is Chair of Biophotonics at the Strathclyde Institute of Pharmacy and Biomedical Sciences at the University of Strathclyde. Following a first degree in Laser Physics and Optoelectronics (1998) and PhD in Physics from the University of Strathclyde (2002), she obtained a Personal Research Fellowship from the Royal Society of Edinburgh (2003) and a Research Councils UK Academic Fellowship (2005), securing a readership in 2008. Since 2004, Gail has received over £9M of research funding from a range of sources including EPSRC, MRC, BBSRC, EU and industry. The work in Gail’s group involves the design, development and application of linear and nonlinear optical instrumentation for biomedical imaging, from the nanoscale to the whole organism. She is a Fellow of the Institute of Physics, and a Fellow of the Royal Microscopical Society
Dr Simon Ameer-Beg
King's College London
Simon Ameer-Beg is a Senior Lecturer in the Cancer Cell Biology & Imaging at King’s College, London. His research interests include: Protein-protein interactions, Multiphoton Fluorescence Lifetime Imaging, Single molecule imaging; FRET, and Fluorescence anisotropy.
Prof Kurt Anderson
Francis Crick Institute
Kurt is a cell biologist who uses advanced imaging methods to study cell migration. He completed his PhD at the University of Salzburg in 1997 on the actin-based mechanism of fish keratocyte migration. He then spent 2 years as a post-doc at the Marie Curie Cancer Research Institute (UK) before moving to Dresden in 2001 to set up the light microscopy facility at the new MPI-CBG. In 2005 he moved to the Beatson Institute for Cancer Research in Glasgow, where he runs the Beatson Advanced Imaging Resource (BAIR) and a research group investigating tumor cell migration. His work at the Beatson used imaging methods such as FRAP and FRET to study the molecular dynamics of cell adhesion and migration in vitro and in vivo. In 2016 Kurt moved to the Francis Crick Institute, where he is now Head of the Crick Advanced Light Microscopy Facility (CALM)
Dr Susan Cox
Light Microscopy Representative infocus Editorial Board
King's College London
Susan is a Royal Society University Research Fellow in the Randall Division of Biophysics at King's College London. Following a PhD in transmission electron microscopy at Cambridge, she spent three years at the National High Magnetic Field Laboratory at Los Alamos looking at the behaviour of the low temperature phases of strongly correlated electron systems. Her current primary interest is the development of new super-resolution localisation microscopy techniques, both through the development of optical systems and the creation of novel image analysis algorithms. She uses these techniques to investigate the behaviour of the cytoskeleton in live cells at the nanoscale. In 2015, Susan was awarded the RMS Medal for Light Microscopy and the President's Medal of the Society of Experimental Biology for the Cell Section.
Dr Ian Dobbie
University of Oxford
Ian is the Facility Manager at Micron Oxford, a multidisciplinary BioImaging Unit working with biomedical researchers in the Oxford area and beyond, located with the Department of Biochemistry at the University of Oxford. Ian has over 15 years’ experience in biological imaging gained in a range of leading academic institutes. He gained a degree in physics and a masters in computer modelling before moving on to do a PhD in muscle mechanics at the Randall Division of Cell and Molecular Biophysics at Kings College London. Since then he has been working in imaging with a range of biological systems at number of world class research centres including, Cancer Research UK, Kings College London and the University of Oxford. Over the last 10 years he has specialised in advanced fluorescence microscopy.
Dr Alessandro Esposito
MRC Cancer Cell Unit
Alessandro’s major focus is to develop new methods for probing and mapping the biochemical events that underlie cellular systems using fluorescence microscopy, with the overall aim of better understanding the fundamental principles that govern tumour suppressive mechanisms and their perturbation in cancer. In his career, Alessandro has developed several technologies (e.g. high throughput FLIM, solid state detectors and imaging specotrpolarimetry) and methods of analysis for quantitative biochemical imaging (FLIM, spectral imaging and anisotropy imaging). Since 2009, he has focused on strategies to enhance the biochemical resolution of fluorescence microscopy and multiplexing several biochemical reactions within the cell with the scope to correlate complex biochemical signatures to cell fate decision and homeostatic control.
Prof Mark Leake
University of York
Since 2013 Mark has been the Chair of Biological Physics in the University of York, and heads the Biological Physics Group. His primary research interest lies in addressing unresolved biological questions, which are intractable with conventional bulk ensemble average methods, by developing new single-molecule microscopy, to advance understanding of native cell biology. His most important independent scientific contribution is the conception/development of multidimensional fluorescence imaging and analytical tools allowing single-molecule characterization in molecular machines in vivo at millisecond time scales, including invention of multicolour ‘slimfield’ super-resolution imaging and photophysical algorithms quantifying molecular composition, architecture and mobility, and is pushing forward the emergence of a new field of ‘single-molecule cellular biophysics.’
Mr Chris Power
Carl Zeiss Ltd
Chris is a 3D Imaging Specialist at Carl Zeiss, UK.
Dr Noah Russell
University of Nottingham
Noah is an Associate Professor in the Faculty of Engineering at the University of Nottingham.
Dr Spencer Shorte
Spencer began his career at the University of Bristol, then left the UK for France where he gained further experience working in neurophysiology. In 1998 he joined the Dept. of Anatomy & Cell Biology, Medical University of South Carolina, USA, as Assistant Professor. He was appointed group leader at the Pasteur Institute in 2001 and created the “dynamic imaging” group. In 2006, he founded and is director of the Institut Pateur Imagopole, an infrastructure harbouring 4 groups with expertise in microscopic, ultrastructural and cytometry based imaging technologies; plus translational research in paradigms relating to infectious pathologies.
Ms Sue Wilson
Leica Microsystems UK
Sue is a Sales Manager for Leica Microsystems UK.
Techniques covered by the Section include: multi-dimensional imaging of live cells, organs and intact organisms; optical tomography; spectroscopic and functional imaging (e.g. FRET, FLIM etc); development of novel methods such as adaptive optics, optical fibres, GRIN lenses; laser-based and solid-state excitation methods; use of multiphoton imaging, confocal and scanning technologies; digital image acquistion, image filtering and analysis; automated and high-throughput imaging systems.
In addition to the overarching aims of the Society, the Section aims to advance optical imaging in the life sciences and physical sciences through education from high-school to advanced academic levels by holding courses, one-day workshops and 2-day specialist scientific meetings.
Sources of help and advice
(Get help with planning and setting up a microscopy facility.)
The confocal listserver and microscopy listserver both provide a useful forum where you can contact other professional microscopists, who may well have the answer(s) that you are seeking.
Hint: set up a separate email account for these listservers – they generate a lot of mail responses.
Local and national networks of imaging professionals can likewise provide help and support. For example, within the UK a list of interested and active microscopy facility managers is maintained on our Facilities Database, in co-operation with BioImaging UK
Our regular events include;
Light Microscopy Summer School
The LM summer school is an annual, residential course at York University which runs over 3 days and covers the principles of light microscopy as well as training participants in practical issues surrounding light microscopy. After introductory presentations, the course is taught predominantly through hands-on practical sessions. The course is suitable for both novices and more experienced users wanting to gain a greater understanding of the microscope.
Getting the most from your Confocal
The course enables students to fully appreciate and utilise the confocal microscope and develop their understanding confocal microscopy background as well as try FRAP, FRET and spectral unmixing. The 2-days consist of short tutorials followed by hands-on practice.
Digital Imaging Processing Workshop
The aim of this one-day workshop is to cover the underlying principles of digital image processing and allow the advanced user of light microscopy to make the very best use of their imaging data. The types of image vary from those of high spatial resolution obtained using confocal microscopy to lower resolution video and multidimensional data obtained using advanced optical techniques (like FRET, FRAP, multiphoton).
Please note that our meetings are aimed at advancing new or under-represented areas of imaging science and technology - They are run "by the members, for the members". Contact us with suggestions for future meetings.