Prof Hahn receives RMS Pearse Prize

Ground-breaking professor wins prestigious RMS award

A ground-breaking professor who has consistently pushed the boundaries with his work examining protein activity within living cells has been nominated for the prestigious Pearse Prize.

Prof. Klaus Hahn has pioneered the design of biosensors and optogenetics to visualize and control signalling in living cells. His work was once rated among the “10 breakthroughs of the decade” by Nature Reviews Molecular Cell Biology.

He will become the latest recipient of the Pearse Prize, which was established in 1982 to honour the contribution made to histochemistry by Professor A G E Pearse.  The award was established by the RMS Histochemistry and Cytochemistry Section (now the Life Sciences Section). It is typically awarded every four to five years to a scientist who has made a significant contribution to histochemistry and life sciences, and is still active in their field. 

Ground-breaking career

Prof Hahn’s seminal Science paper (2000) was ground-breaking in the use of optical tools to detect localised Rac activation and has been cited 676 times. Subsequent Nature  and Science papers (2004, 2006, two in 2009, 2015 and 2016) led to a step change in the understanding of Rho family GTPase activation, function and spatio-temporal regulation in living cells.

The Thurman Distinguished Professor of Pharmacology is also founder and director of the UNC-Olympus Imaging Center. His lab continues to work at the cutting edge, developing novel molecular probes based on engineering allosteric networks in proteins. His work continues to benefit a whole generation of researchers - exemplified by the number of collaborative projects Prof. Hahn engages with and the high level of overall citation.

He is set to receive the accolade in July at the mmc2019 Congress, where he will also be giving a plenary talk.


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