Jacob Pattem

Biomaterials at the University of Cardiff, Wales, UK

Dr Jacob Pattem is a multidisciplinary biophysical scientist whose research lies at the interface of physics, micro-to-molecular biology, and nanotechnology. He utilizes advanced multiscale, 5-dimensional correlative AFM-based microscopy approaches (X, Y, Z imaging, force, and time), revealing structure-function relations in human, animal and plant health and disease. His research focuses on unravelling molecular informed mechanisms that underpin biophysical responses to complex biological processes such as dental erosion, single-cell microbial colonization, biofilm control, mucus barrier modulation, gene-structure function in plant health and alternatives to anti-microbial resistance in infection. Throughout this he has always aimed at conducting research with the goal of clinical translation for patient benefit, particularly, those suffering from debilitating health conditions and 3rd world rural communities with poor access and reluctance to treatment.