Session 2 Dynamics by SPM
Simon Scheuring is Distinguished Professor of Anesthesiology Research in the Department of Anesthesiology at Weill Cornell Medicine in New York, USA. He is also Professor of Biochemistry and Biophysics at Weill Cornell Medicine in New York, USA.
He is a trained biologist (Biozentrum, University of Basel, Switzerland). During his MSc and PhD, he learned electron microscopy (EM) and atomic force microscopy (AFM) for the structure determination of membrane proteins such as aquaporins and sugar transporters. During his postdoc and as research assistant (Institut Curie, Paris, France), he learned membrane physical chemistry and developed AFM for the study of native membranes and ventured into setting up his lab as a junior research director at the Institut Curie. Promoted to senior research director, he built a larger laboratory in Marseille (INSERM / Aix-Marseille Université, France). In 2017, he moved to Weill Cornell Medicine, where he got appointed as Professor in the Department of Anesthesiology (WCM, New York, USA). Simon Scheuring’s laboratory develops and applies AFM-technologies for the study of membrane phenomena, such as membrane protein structure, assembly, diffusion, and conformational dynamics of unlabeled single molecules, bridging structure and function. Over the past years, his laboratory has been instrumental in the development of High-Speed AFM (HS-AFM) methods, extracting quasi-atomic structural details from single molecule AFM data, and reaching millisecond temporal resolution for the analysis of conformational dynamics. In recent works, his laboratory combines HS-AFM with cryo-EM to acquire an integrated understanding of the dynamics and structures of membrane proteins.