Core Imaging Facility serving the Cambridge Stem Cell Institute
The Babraham Institute Flow Cytometry Core Facility offers high quality service and state-of-the-art instrumentation to members of Babraham Institute and external users
The BI Imaging Facility has a wide variety of imaging platforms. These are high-specification commercial systems that have been configured to accommodate a broad range of applications with both fixed and live specimens. Systems include point-scanning confocal (Leica Stellaris 8, Nikon A1-R, Zeiss 780), spinning disk confocal (Olympus SpinSR), multi-photon (Zeiss LSM-7 with Coherent Chameleon Vision+MPX), TIRF (Nikon), wide-field (Nikon, Olympus and Incucyte), High/Ultra-High Content (Molecular Devices HT.ai and Miltenyi MACSima), Super Resolution (Nikon N-SIM/N-STORM) and laser micro-dissection (Zeiss MicroBeam). To complement fluorescence imaging capabilities, the Facility has a Zeiss CrossBeam 550 FIB SEM which offers various modalities for electron microscopy, including high resolution volumetric EM.
The Cambridge Advanced Imaging Centre combines core imaging facilities with an advanced technology development capability. The centre offers both advanced electron and light microscopy services and is open to internal and external users. Staff in the centre have diverse expertise from physics to computer science and cell biology.
The CIMR Flow Cytometry Core Facility provides flow cytometry analysis and cell sorting services to members of the CIMR, colleagues at the University of Cambridge and external users.
The core provides state-of-the-art imaging resources, training courses for scientists and students and development of new imaging systems as well as user-friendly analysis and acquisition tools for specific research applications and cancer diagnostics. Stefanie Reichelt, teaches at Cambridge University, in scientific workshops and out-reach events and is founder of the Plymouth Advanced Microscopy Course.
The Gurdon Institute Imaging Facility focuses on light microscopy. We provide access to a variety of imaging technologies including confocal, multi-photon, high content screening, and super-resolution microscopy. The facility comprises four members of staff with specialised expertise in all stages of the imaging workflow from experimental design to computational analysis. We provide support for imaging experiments and carry out research in collaboration with developmental and cancer biologists.
The Microscopy Core Facility is a research facility serving both the SLCU and departments and institutes across Cambridge. Our expertise covers a range of imaging and analytical tools developed for the plant sciences.
LMB Electron Microscopy Facility comprises a series of state-of-the-art electron microscopes and specimen preparation equipment, focusing on electron cryo-microscopy (cryoEM) of unstained biological material. We have 4x 300keV Krios TEMs, 1x 200keV Glacios TEM, 2x cryo-FIB-SEMs and other low voltage TEMs and SEM. We do training or cryoEM data collection for users. We are actively involved in research on cryoEM methodology, technical development, and research projects on structural biology.