Expertise
Imaging Platforms
Keywords - ELECTRON MICROSCOPY: Transmission EM, Electron tomography, Scanning EM (FEG), Focused Ion Beam SEM, Integrated Light and SEM, Cryo-ET, Scanning Transmission EM, Scanning EM (Tungsten), Serial Block Face SEM, Integrated Light and TEM, Cryo-TEM
Applications
Keywords - BIOLOGICAL: CELL BIOLOGY, HISTOLOGY/PATHOLOGY, NEUROBIOLOGY
Structrual Biology
SAMPLE PREPARATION
KEYWORDS - MATERIALS: FOCUSED ION BEAM (OTHER)
Thin-film liquid layer plung-freezing
High-pressure freezing
Data Analysis
Keywords - Software: IMOD, AMIRA, DIGITAL MICROGRAPH/GMS Relion, mrc, cryosparc
KEYWORDS - HARDWARE: CRYOEM, SPA, CRYO-ET, FIBSEM, CRYO LAMELLA MILLING
Single particle analysis (SPA) and 3D structural reconstruction.
Cryo-tomgrapgy data processing and 3D structural reconstruction.
Shared Access
For collaboration users
Funding
UKRI, MRC (Medical Research Council)