infocus #53 March 2019 Brillouin Microscopy - Measuring Mechanics in Biology Using Light

Mechanical properties of cells and tissues have been shown to play a crucial role in development and disease, but standard techniques for probing them are usually invasive and limited to the sample’s surface.

DOI:  10.22443/rms.inf.1.171

Brillouin microscopy is an emerging optical technique that enables non-contact measurement of viscoelastic properties of a material with diffraction-limited resolution in 3D. It exploits Brillouin scattering; the interaction between light and acoustic waves.