Susan Cox
Talk title: Deep learning for data synthesis in fluorescence microscopy
Susan is a Royal Society University Research Fellow in the Randall Division of Biophysics at King's College London. Following a PhD in transmission electron microscopy at Cambridge, she spent three years at the National High Magnetic Field Laboratory at Los Alamos looking at the behaviour of the low temperature phases of strongly correlated electron systems. Her current primary interest is the development of new super-resolution localisation microscopy techniques, both through the development of optical systems and the creation of novel image analysis algorithms. She uses these techniques to investigate the behaviour of the cytoskeleton in live cells at the nanoscale. In 2015, she was awarded the RMS Medal for Light Microscopy and the President's Medal of the Society of Experimental Biology for the Cell Section.
Izzy Jayasinghe
Izzy’s research focuses on the development of novel optical analytical tools to enable better histopathological diagnostics, multi-scale imaging, and in situ omics. One of the key areas of active, ongoing work is the development of super-resolution microscopy techniques for medical and biological investigations, for visualising sub-cellular structures such as protein clusters, organelles, and disease markers. The lab is also interested in developing novel imaging probes such as nondescript fluorescent labels and photoluminescent nanodiamonds, using advanced manufacturing methods such as 3D printing, custom optics, optical 3D modelling and novel camera technologies to develop new microscopes and microscopy protocols that are accessible, versatile, and tailored to various medical and bioimaging applications.
Deirdre Kavanagh
Deirdre studied Medical Microbiology and Infection at the University of Edinburgh before completing an interdisciplinary PhD in Electrical Engineering on the subject of Microfluidics for Non-Invasive Prenatal Diagnostics. During her postdocs, she applied advanced fluorescence microscopy and spectroscopy to study the molecular mechanisms underlying cell communication and trafficking. Deirdre went on to work as an Imaging Specialist at University of Birmingham, where her primary role was in the teaching and training of researchers in advanced microscopy. In 2021, she joined the University of Oxford as Microscopy Facility Manager for the Biochemistry Department where she is responsible for the running of a busy microscopy facility and continues her passion for microscopy teaching and training. She has expertise in fluorescence microscopy with specialist interest in super-resolution, FCS and light-sheet technologies.
Lothar Schermelleh
Lothar’s research aims at understanding the relationship between 3D nuclear organisation and genome activity in mammalian cells by combining genetic tools and innovative live-cell and correlative super-resolution imaging and analysis approaches. This will ultimately enable to directly observe genome activity, such as transcription, replication and repair, in the context of the nuclear environment at the nanoscale. As an affiliated member of the Micron Advanced Bioimaging Unit, Lothar is driving the development of computational analysis and fluorescence labelling tools for super-resolution microscopy.
Ali Shaib
Ali is a post-doctoral researcher in the Rizzoli lab, which has a dual focus on the development of high-end imaging and synaptic physiology. The lab’s projects combine super-resolution imaging techniques (STED, STORM, expansion microscopy) with conventional imaging, electron microscopy and quantitative biochemistry. The lab has a strong history of developing new imaging tools, ranging from new chemical probes to camelid-derived single-chain antibodies (nanobodies), which result in the improved visualization of cellular targets, especially at the nanoscale. Ali specialised in complex sample applications for super-resolution techniques and in expansion microscopy.
Christophe Zimmer
Christophe leads the Imaging and Modeling Unit of the Institut Pasteur, which develops computational and experimental approaches to characterize and quantitatively predict selected cellular processes. Current projects concentrate on : (i) investigating the dynamic spatial architecture of the genome and its functional consequences, and (ii) developing high resolution or high throughput imaging techniques, and applying them to study genome architecture and the cell biology of pathogens, especially HIV. The lab mobilizes a spectrum of expertise including biophysics, microscopy, informatics and cell biology, and works in close collaboration with several experimental groups, many of them at Institut Pasteur.