25 Feb 2026

New special issue of Journal of Microscopy – Microscopy and Infectious Diseases

The Journal of Microscopy is pleased to announce the publication of a new special issue, Microscopy and Infectious Diseases!

The special issue, guest edited by Leandro Lemgruber (University of Glasgow, UK) and Mariana De Niz (Northwestern University, USA), emphasises the interconnection between microscopy and microbiology, advancing understanding of infectious diseases.

In the introductory article, the Guest Editors say: “The topic of Microscopy and Infectious Diseases has been one of great interest to us as editors, throughout our careers as parasitologists and as imaging scientists. Research on infectious diseases is vast, covering organisms including viruses, bacteria, fungi, and parasites. These fascinating microorganisms range from viruses of a few nanometers to parasitic helminths of several meters of length.

“Within this range, microscopy has been pivotal to our understanding of infectious microorganisms including their complex life cycles, cell biology, immune evasion mechanisms, and host-pathogen interactions, among others. The fields of microbiology and imaging have historically significantly impacted each other, with pioneering technologies enabling us to understand ever more complex processes, and to ask questions that often require the generation of novel tools.”

 

Introduction to special issue on Microscopy and Infectious Diseases

Mariana De Niz, Leandro Lemgruber

Imaging malaria parasites across scales and time

Julien Guizetti

Advances, challenges, and applications of cryo-electron tomography workflows for three-dimensional cellular imaging of infectious pathogens

Moara Lemos, Ingrid Augusto, Wanderley De Souza, Kildare Miranda

Optimisation of freeze substitution protocols for the examination of malaria parasite structure by volumetric electron microscopy

Rachel Rachid, Camila Wendt, Wanderley de Souza, Kildare Miranda

A comparison of super-resolution microscopy techniques for imaging tightly packed microcolonies of an obligate intracellular bacterium

Alison J. North, Ved P. Sharma, Christina Pyrgaki, John Lim S.Y., Sharanjeet Atwal, Kittirat Saharat, Graham D. Wright, Jeanne Salje

Ultrastructure expansion microscopy: Enlarging our perspective on apicomplexan cell division

Sofía Horjales, Florencia Sena, María E. Francia

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

Heidi Anderson, Rhonda Reigers Powell, Meredith Teilhet Morris

Microfluidic live-cell imaging of Aspergillus fumigatus and Candida albicans hyphal growth treated with AmBisome and Caspofungin

D. D. Thomson, R. Inman, S. Nye, E. M. Bignell

Modulation of host cell membrane biophysics dynamics by Neospora caninum: A study using LAURDAN fluorescence with hyperspectral imaging and phasor analysis

Marcela Díaz, Carlos Robello, Andrés Cabrera, Leonel Malacrida

Traction force generation in Plasmodium sporozoites is modulated by a surface adhesin

Johanna Ripp, Dimitri Probst, Mirko Singer, Ulrich S. Schwarz, Friedrich Frischknecht

Artificial intelligence-powered microscopy: Transforming the landscape of parasitology

Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis