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GW4 Facility for High-Resolution Electron Cryo-Microscopy

The GW4 cryoEM Facility enables the visualization of organic and biological specimens at near-atomic levels of detail. Our comprehensive range of services covers every aspect of the cryoEM workflow, from the preparation of vitrified samples to screening, optimization, high-resolution data generation, and computational processing for structure generation. Our facility is equipped with the FEI Talos Arctica electron cryo-microscope, a Gatan energy filter, and a K2 direct electron detector.



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Expertise 

Imaging Platforms 

Keywords - Electron Microscopy: Transmission EM, Electron tomography, Cryo-ET, Cryo-TEM

 

 


 

Applications 

Keywords - Biological: Cell Biology, Microbiology, Immunobiology, Bio-materials
Keywords - Physical Sciences: Nanomaterials, Composites

 

Sample Preparation

Keywords - Biological: Plunge freezing

 

Data Analysis

Keywords - Software: Digital Micrograph/GMS
KEYWORDS - HARDWARE: TALOS ARCTICA, K2, ENERGY FILER, VITROBOT
OTHER: RELION, CRYOSPARC

 

Funding Overview

Wellcome Trust, BBSRC

 



Point of Contact

GW4 Facility for High-Resolution Electron Cryo-Microscopy
Life Sciences Building
University of Bristol
Bristol, BS8 1TQ, United Kingdom


Point of Contact 

Ufuk Borucu

Email: GW4-cryoEM@bristol.ac.uk