Expertise
Imaging Platforms
Keywords - X Ray microscopy : MicroCT
Skyscan 1272 desktop high-resolution micro-CT scanner:
- More than 200 Megapixel (14450 x 14450 pixels) in every virtual slice through objects
- More than 2600 such slices can be reconstructed after a single scan
- Due to phase-contrast enhancement, object details down to 0.4um can be detected
- Maximum scanning diameter - 75mm, integrated micropositioning stage
- 2D/3D image analysis, surface and volume rendering
Applications
Keywords - Biological: Cell Biology | Developmental Biology | Histology/Pathology | Zebrafish | Drosophila | Bio-materials | Bone | Teeth
Keywords - Physical Sciences: Bioengineering & Biomaterials | Geology/Mineralogy | Composites | Polymers & Organic Electronics
The micro-CT facility is commonly used to scan, analyse and create 3-D models of:
- bone and teeth
- medical implants, such as stents
- tissue engineering samples, such as scaffolds
- pharmacology, such as tablets
- geology samples, such as soil
- printing, such as 3-D model creating for 3-D printing
Common parameters of analysis are structure volume, thickness, number, separation, connectivity, density and porosity.
Samples can also be modelled in 3-D, and images and movies created.
Sample Preparation
Samples can be scanned wet or dry, fixed or fresh
Data Analysis
Keywords - Software: ImageJ | Skyscan CTAnalysis | Skyscan CTVox | Drishti 3-D Modelling
We have two workstations dedicated to sample analysis and one workstation dedicated to volume rendering and 3-D modelling.
Shared Access
Available to Sheffield University staff and students. Access to other academic or industrial researchers by arrangement.
Funding
The facility is maintained from user access charges. The Scanner and computers were funded through Bloodwise, Yorkshire Cancer Research and Sheffield Hospitals Charity.