Life Sciences

Fluorescent nanodiamonds (FNDs) are emerging as efficient and safe candidates for cellular imaging, due to their bright fluorescence, high photostability with sufficiently long lifetime, and excellent biocompatibility. For in vivo work, FNDs have been recognized as a safe and biocompatible material in many studies. Amerigo Scientific provides nanodiamonds featuring three distinct fluorescence properties: NV centers emitting red-to-near-infrared fluorescence, NVN centers exhibiting green fluorescence, and novel hybrid particles containing both NV and NVN centers within a single structure, which display visible yellow fluorescence. These hybrid particles enable ratiometric fluorescence calibration by monitoring the intensity ratio between green and red spectral emissions. This capability facilitates particle tracking even under conditions of high background fluorescence.
To power up imaging with precision, Amerigo Scientific’s range of bioconjugated FNDs is engineered in multiple sizes (40–140 nm), having an outstanding profile of uniformity, stability, and scalability, enabling researchers to select optimal dimensions for specific imaging depths and resolutions. Smaller particles excel in single-molecule tracking, while larger variants enhance contrast in deep-tissue imaging. If small particles are necessary for research, 40nm particles could be the best choice in terms of both brightness and size. For initial users, it is generally advised to begin with larger particle sizes (approximately 100 nm or above) to assess whether fluorescent nanodiamonds can deliver sufficient contrast for the intended application.
In conclusion, Amerigo Scientific offers highly sensitive, precision-engineered fluorescent nanodiamonds tailored for advanced imaging applications. Its FNDs combine exceptional brightness, photostability, and biocompatibility, making them ideal for demanding research in super-resolution microscopy, single-molecule tracking, and deep-tissue imaging. With rigorous quality control, Amerigo ensures batch-to-batch consistency, critical for reproducible experiments. Whether for high-resolution studies or deep imaging, Amerigo Scientific provides reliable, cutting-edge FND solutions backed by strong technical support, accelerating breakthroughs in life sciences and nanomedicine.

Created: 26 May 2025 03:05:27 AM