A one-day meeting to promote synergy and further engagement across the biological and physical sciences. This meeting focuses on advances in microscopy research emerging at the frontiers between physics and biology, covering the progress and challenges in imaging biological materials and opportunities for low-dose imaging in cryogenic and liquid conditions enabled by new instrumentation in the physical sciences. Recent developments associated with atomistic modelling of molecular systems and data analysis of large volumes will also be presented. The meeting will provide opportunities for established researchers and students to present their work and know-how with the aim to promote networking and future collaboration in this fertile and exciting multidisciplinary field across the interface between the biological and physical disciplines.