University of Edinburgh
University of Newcastle
Katrina Crompton completed her Master’s in Mathematics before studying for a PhD in Biosciences at Newcastle University supervised by Adam Wollman. In her research she develops new microscopes including single-molecule fluorescence and instruments designed to work in extreme environments, including microgravity.
University of York
Sarah is a PhD student in the University of York Physics of Life group supervised by Steven Quinn and Mark Leake. She is studying the effects of molecular crowding and other environmental changes on biomolecules using single-molecule FRET microscopy techniques. Specifically work so far has focused on DNA hairpins and their opening and closing dynamics and the SARS-CoV-2 pseudoknot which acts as the stimulatory sequence for frameshifting in the virus.
University of Birmingham
Dirk-Peter Herten is a Chair in Cell Biology of Membrane Proteins at the University of Birmingham shared by the Institute of Cardiovascular Sciences and the School of Chemistry with his labs located in the Institute of Biomedical Research (IBR).
Dirk’s interdisciplinary research spans from microscopy techniques over switchable fluorescent probes to biological applications, like T-cell signalling in the context of inflammation. He has specialized in single-molecule microscopy enabling quantitative studies of the composition and dynamics of cellular structures and enzymatic reactions in living cells.
University of Warwick, UK
Dr Séamus Holden studies bacterial cell biology and biophysics using super-resolution microscopy and other advanced imaging methods. His primary biological focus is how bacteria remodel their cell wall, which is one of the most important targets for antibiotics.
Séamus studied Physics at the University of Oxford, followed by a DPhil in single molecule biophysics in the laboratory of Professor Achilles Kapanidis at Oxford. In 2011 he joined the laboratory of Professor Suliana Manley at EPFL as a post-doc, where he was a Marie Skłodowska-Curie Intra-European Fellow. In 2015, he started his own lab at the Centre for Bacterial Cell Biology, Newcastle University. In 2017 Séamus was awarded a Wellcome Trust & Royal Society Sir Henry Dale Fellowship to study physical principles of bacterial cell division and in 2020 he was awarded the British Biophysical Society Louise Johnson Early Career Award for “his work applying ground-breaking concepts in optical microscopy to study bacterial cell biophysics”. In 2022 he moved to the University of Warwick as an Associate Professor (Reader).
University of Birmingham
Tamara is a postdoc in the group of Professor Davide Calebiro at the University of Birmingham, where she is using fluorescence-based single-molecule microscopy to study conformational dynamics of beta-arrestins, intracellular proteins interacting with G protein-coupled receptors (GPCRs). Before moving to the UK, Tamara completed her PhD in structural biology at the Paul Scherrer Institute in Switzerland, investigating molecular mechanisms of biased signalling in cannabinoid CB2 receptor.
University of Leeds
Aleks obtained a PhD in Mechanical Engineering at Imperial College London, where he applied novel fluorescence microscopy techniques to study confined fluids. He then moved to the Chemistry department in Cambridge, where he worked on new single-molecule and light-sheet microscopy tools for investigating the behaviour and organisation of membrane proteins in T cells. In 2020, Aleks starts his own lab as a University Academic Fellow at the Bragg Centre for Materials Research in Leeds. Here, his lab will focus on the application of high-speed fluorescence imaging to push beyond the temporal limits of single-molecule and super-resolution fluorescence microscopy.University of Leeds
Amir is a physicist with a background in optics. His current research interests include developing a fast and single-molecule sensitive fluorescent-activated cell sorting (smFACS) technique employing high-resolution oblique plane microscopy. In addition, Amir has a keen interest in single-molecule localisation microscopy, with a particular focus on investigating the cellular nanoscale dynamics and structure. Prior to commencing his doctorate program at the University of Leeds in 2021, Amir engaged in super-resolution microscopy at various esteemed research institutes worldwide.University of Sheffield
Dr Tom Sheard's current research harnesses expansion microscopy and proteome labelling strategies to visualise nanoscale subcellular compartments in a variety of life science projects. Tom completed a Ph.D. in biophysics and cardiac biology at the University of Leeds, where he used expansion microscopy to characterise pathological remodelling to calcium-signalling nanodomains in heart failure. In 2016 Tom obtained an MPhil degree in Adaptive Organismal Biology at the University of Manchester, where he applied electron tomography to characterise the layout of calcium signalling structures in avian hearts.