After some 350 years, newly discovered Leeuwenhoek microscopes are emerging. Two have now been subject to examination with the scanning electron microscope (SEM).
Fluorescence microscopy is an essential tool in cell biology as it allows scientists to look at what is inside of a cell and easily see the organisation of organelle by labelling different organelles selectively.
Supported by an RMS Summer Studentship award, I spent time in the lab of Professor Duncan Graham at the University of Strathclyde to study the uptake and distribution of Bruton’s tyrosine kinase (Btk) inhibitors, ibrutinib, acalabrutinib and ibrutinib-yne using a combination of Raman and stimulated Raman scattering microscopy.
Through the loan of a portable Scanning Electron Microscope (SEM), this successful outreach programme focuses on bringing research directly to schools.
With the dust now settled on mmc2023 (incorporating EMAG 2023), we take a look back at what proved to be a fantastic few days in Manchester, celebrating the very best in microscopy, imaging and flow cytometry.
Brightfield microscopy has been a viable observation technique for cytology and histological analysis employing stained cells and tissue sections mounted on a microscope slide.
We are now just weeks away from mmc2023 (incorporating EMAG 2023) kicking off in the wonderful and vibrant city of Manchester, UK, and the excitement is well and truly building ahead of the RMS’s flagship event.
Having first been put forward as a sample preparation tool in 2015, expansion microscopy is something of a ‘new kid on the block’ in scientific research.
Optical microscopy has used the same manufacturing methods for milling and sanding glass elements to produce high-quality optics for over a century. Recent developments in 3D printing have opened the possibility of printing optical components, but the surface quality of these 3D prints remains unknown.
During the early days of the RMS, its (mainly wealthy) gentlemen, since women weren’t allowed to attend, would meet regularly, when members would discuss their latest microscopes and share some of their observations, which would most likely be hand-drawn at the time.
